Overview
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The intervention phase of Project Corbett is a randomized controlled trial to evaluate the efficacy of a one-year long, evidence- and clinical experience-based intervention to improve motor function and reduce the severity of motor delays in infants who have been admitted to a Neonatal Intensive Care Unit (NICU).
Subject Population
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NICU admission and qualifies for Early Childhood Clinic (NICU high-risk follow up clinic) or Early Intervention due to:
- BW <1500 grams
OR
- Disorders of the central nervous system
- Brain injury (including but not limited to extra axial hemorrhage, any grade intraventricular or intraparenchymal hemorrhage, stroke, hypoxic ischemic encephalopathy (HIE), meningitis)
- HIE includes mild, moderate, severe exam on modified Sarnat exam, both cooled and non-cooled
- includes “at risk for HIE” with 10-minute Apgar <7 plus pH<7.15 or base deficit >/=12.
- Brain developmental abnormalities (hydrocephalus, microcephaly, cortical dysgenesis)
- Cramped synchronous movements at term PMA
- Brain injury (including but not limited to extra axial hemorrhage, any grade intraventricular or intraparenchymal hemorrhage, stroke, hypoxic ischemic encephalopathy (HIE), meningitis)
OR
- Bronchopulmonary dysplasia (BPD) defined as need for respiratory support at 36 weeks postmenstrual age in an infant born at <32 weeks of gestation.
AND
- Medically stable, AND able to start intervention between 34-48 weeks PMA.
Study Personnel
Mentioned Profile
Arun Jayaraman, PT, PhD
Executive Director, Technology & Innovation Hub (tiHUB); Director, Max N?der Center for Rehabilitation Technologies & Outcomes 嫩B研究院Study Partners
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Lurie Children's Hospital
Prentice Women's Hospital
Children's Hospital at the University of Illinois
Funding Source
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Patrick G. and Shirley W. Ryan Foundation