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Multiple Sclerosis (MS):

(Penner et al, 2009; n = 309 MS patients and 147 healthy controls in the validation study)

• Excellent test retest reliability for total, motor and cognitive (r = 0.86; r = 0.86; r = 0.85)

Multiple Sclerosis:

(Penner et al, 2009)

• Excellent FSMC convergent correlation with fatigue severity scale (FSS), (r = 0.797) and the modified fatigue impact scale (MFIS) (r = 0.829)
• Adequate convergent correlation with the neurologist¡¯s rating of fatigue (r = 0.508)
• Poor FSMC-motor convergent correlation the MSFC-9HPT and -25FTW (r = 0.22)
• Adequate FSMC-motor convergent correlation with the EDSS (r = 0.38) 
• Excellent FSMC-motor convergent correlation with the MSIF-motor (r = 0.804) 
• Poor FSMC-cognitive convergent correlation with the paced auditory serial addition test (PASAT), (r = 0.27) 
• Excellent FSMC-cognitive convergent correlation with the MSIF-cognitive (r = 0.832) 
• Adequate FSMC total score, FSMC-motor and FSMC-cognitive convergent correlation with depression measured by the Beck Depression inventory (r = 0.49, r = 0.42, and r = 0.47)

Multiple Sclerosis:

(Penner et al, 2009) 

• FSMC total score had 88.7 sensitivity and 83.7 speficificity in differentiating pwMS from healthy controls, the FSMC-motor score had slightly higher sensitivity (89.0) and speficificty (86.4) using logistic regression, these values were higher than those found for either MSIF (sensitivity = 87.1, specificity = 71.4) or the FSS (sensitivity = 86.7, specificity = 69.4)