ÄÛBÑо¿Ôº

Nephrotic Syndrome: Selewski et al, 2017; n=127; Age Range=8-17; Severity= active nephrotic syndrome

• MID = 3 points

Juvenile Idiopathic Arthritis

Morgan et al 2017; n=4; Age Range=15-20; Severity = no problems/mild problems, mild/moderate problems, moderate/severe problems

Diverse Patient Sample

Dewitt et al, 2011; n=3048; age=8-17; Diverse Sample of Pediatric Patients

     - Mean (SD) Pediatric PROMIS; 50 (10)

Nephrotic Syndrome: Selewski et al, 2017; n=127; Age Range=8-17; Severity= active nephrotic syndrome

• Baseline
  • Mean score (n=127): 46.3(9.2)
• Event visit [occurred after remission or 3-months post baseline]
  • Mean score (n=112): 50.8 (9.5)
• Final visit [12-months post-baseline]
  • Mean score (n=90): 52.4 (9.2)

Cerebral Palsy: (Kratz et al, 2013; n=97; Age = 12.67 (2.96); Children with Cerebral Palsy who were going to have eligible surgery)

Short form

• Mean score: 41.43
• Median score: 40.00

CAT

• Mean score: 43.38
• Median score: 42.80

General population: (Varni et al, 2014; n=331; age= 12.1; General Pediatrics)

• Excellent test-retest Reliability for short form (ICC = .73)
• Excellent test-retest Reliability for CAT (ICC = .72)

Cerebral Palsy: (Kratz et al, 2013; n=97; Age = 12.67 (2.96); Children with Cerebral Palsy who were going to have eligible surgery), short form

     - Adequate internal consistency for PROMIS Mobility SF (14-59)  (Cronbach Alpha = .75).

General population: (Varni et al, 2014; n=331; age= 12.1; General Pediatrics)

• Adequate internal consistency (¦Á=.73-.74)

Childhood-Onset Systemic Lupus Erythematosus (SLE)

Jones, 2017; n=100 (at visit baseline); Age=15.8?(2.2)

• Excellent internal consistency for PROMIS-Short Form pooled across all visits: (Cronbach¡¯s Alpha = 0.93)

Cerebral Palsy: Kratz et al, (2013)

Pearson bivariate correlation coefficients for PROMIS^? and legacy measures of mobility

*Child Self-report
**Parent report
***Performance Based

Nephrotic Syndrome: Selewski et al, 2017; n=127; Age Range=8-17; Severity= active nephrotic syndrome

• • Adequate correlation with Peds QL Physical Functioning (¦Ñ=.60)
  • Poor correlation with Peds QL Emotional Functioning (¦Ñ=.39)
  • Poor correlation with Peds QL Social Functioning (¦Ñ=.45)
  • Poor correlation with Peds QL School Functioning (¦Ñ=.37)
  • Adequate correlation with overall health-related QOL (¦Ñ=.60)

 Childhood-Onset Systemic Lupus Erythematosus (SLE)

Jones, 2017; n=100 (at visit baseline); Age=15.8?(2.2)

Bivariate correlation (r_pool) between pediatric PROMIS short forms and legacy measure subscalesa

• ^a Values are the pooled correlation coefficients (r_pool) across visits (n?=?280 patient visits). PROMIS?=?Patient©\Reported Outcomes Measurement Information System; SLEDAI©\2K?=?Systemic Lupus Erythematosus Disease Activity Index 2000; BILAG?=?British Isles Lupus Assessment Group index; MD©\global?=?physician global disease assessment; SDI?=?Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index; PedsQL©\GC?=?Pediatric Quality of Life Generic Core Scale 4.0; PedsQL©\RM?=?Pediatric Quality of Life Rheumatology Module 3.0; SMILEY?=?Simple Measure of Impact of Lupus Erythematosus in Youngsters; C©\HAQ?=?Childhood Health Assessment Questionnaire; CHQ©\PF50?=?Child Health Questionnaire with 50 questions.
• ^b Scoring: A?=?12, B?=?8, C?=?1, D?=?0, E?=?0.
• ^c On a 10©\point Likert scale, where 0?=?inactive disease.
• ^d Range 0¨C47, where 0?=?absence of damage.
• ^e P?<?0.001 and r?>?0.30.

Cerebral Palsy: (Kratz et al, 2013)

• No Floor effects for either the PROMIS Mobility SF (14-59) or the PROMIS Mobility CAT (20-80).
• Adequate ceiling effect (N=6, 7.2%) for PROMIS Mobility SF (14-59)
• Adequate ceiling effect (N=2, 2.5%) for PROMIS Mobility CAT (20-80).

General population: (Varni et al, 2014; n=331; age= 12.1; General Pediatrics)

• Effect size: .37 to .38