Parkinson’s Disease:
(Hackney & Earhart, 2010; n = 78; mean age = 65.1(9.5) years, female: 28%; Disease duration = 8.2(5) years; Hoehn and Yahr scores range: 0.5-3 (0.5 = 1, 1 = 1, 1.5 = 11, 2 = 49, 2.5 = 8, 3 = 8); Matched with age- and sex-matched controls:n = 74; mean age = 65.0(10.0), female: 23%)
Table 1: Spatiotemporal Gait Parameters of Forward and Backward Walking
|
Forward Walking
|
|
Backward Walking
|
|
|
PD
|
Control
|
PD
|
Control
|
Velocity (m/s)
|
1.2 m/s ± 0.2?
|
1.2 m/s ± 0.2?
|
0.7 m/s ± 0.2*
|
0.9 m/s ± 0.2
|
FAP
|
92.7 ± 1.1*?
|
96.9 ± 1.1?
|
60.4 ± 1.1*
|
74.2 ± 1.1
|
Stride Length (m)
|
1.3 ± 0.01*?
|
1.4 ± 0.01?
|
0.7 ± 0.01*
|
1.0 ± 0.01
|
Base of Support (m)
|
0.1 m ± 0.04
|
0.1 m ± 0.04
|
0.2 m ± 0.04
|
0.2 m ± 0.04
|
Cadence (steps/min)
|
109 ± 1.4
|
105 ± 1.4
|
112 ± 1.4
|
105 ± 1.4
|
Swing %
|
34.5 ± 0.3*?
|
35.7 ± 0.3?
|
31.4 ± 0.3*
|
34.8 ± 0.3
|
Double Support %
|
31.3 ± 0.8?
|
28.7 ± 0.8?
|
39.3 ± 0.8*
|
32.0 ± 0.8
|
Stance %
|
65.5 ± 0.3*?
|
64.3 ± 0.3?
|
68.8 ± 0.3*
|
65.2 ± 0.3
|
|
|
VARIABILITY
|
|
|
Stride Length SD(m)
|
0.05 ± 0.006
|
0.05 ± 0.006
|
0.09 ± 0.006
|
0.09 ± 0.006
|
Swing % SD
|
2.1 ± 1.3
|
1.9 ± 1.4
|
7.4 ±1.3
|
4.9 ± 1.4
|
Stance % SD
|
3.0 ± 0.7?
|
3.2 ± 0.7
|
8.0 ± 0.7*
|
5.0 ± 0.7
|
Values are Means ± SE
*Significant difference between groups within walking condition
?Significant difference between FW and BW within group
Table 2: Spatiotemporal Gait Parameters in Freezers (n = 35) versus Non-Freezers (n = 43)
|
Forward Walking
|
|
Backward Walking
|
|
|
Freezers
|
Non Freezers
|
Freezers
|
Non Freezers
|
Velocity (m/s)
|
1.1 ± 0.04
|
1.2 ± 0.04
|
0.61 ± 0.05
|
0.73 ± 0.05
|
FAP
|
91.4 ± 7.9
|
93.7 ± 8.2
|
55.8 ± 2.2?
|
64.1 ± 2.5
|
Stride Length (m)
|
1.2 ± 0.03
|
1.3 ± 0.03
|
0.7 ± 0.04?
|
0.8 ± 0.05
|
Base of Support (m)
|
0.1 ± 0.007
|
0.1 ± 0.005
|
0.2 ± 0.01
|
0.2 ± 0.01
|
Cadence (steps/min)
|
109 ± 2.4
|
109 ± 1.7
|
114 ± 4.7
|
110 ± 3.5
|
Swing %
|
33.7 ± 0.42*
|
35.2 ± 0.34
|
30.3 ± 0.8*
|
32.4 ± 0.6
|
Double Support %
|
32.8 ± 0.84*
|
30.0 ± 0.70
|
41.2 ± 2.3
|
37.8 ± 11.6
|
Stance %
|
66.4 ± 0.42*
|
64.8 ± 0.34
|
70.0 ± 0.9?
|
67.7 ± 0.6
|
|
|
VARIABILITY
|
|
|
Stride Length SD(m)
|
0.06 ± 0.04
|
0.05 ± 0.04
|
0.1 ± 0.01
|
0.1 ± 0.01
|
Swing % SD
|
2.5 ± 0.2?
|
107 ± 0.1
|
8.6 ± 3.2?
|
6.4 ± 2.8
|
Stance % SD
|
3.7 ± 0.4?
|
2.5 ± 0.1
|
10.8 ± 3.0?
|
5.7 ± 0.5
|
Values are Means ± SE. Independent t-tests were used to test for significant differences between groups
*Significant difference between freezers and non-freezers
?Significant difference with Mann Whitney Rank Sum test